The list of radiopharmaceuticals covers not only those used in the practice of nuclear medicine, but also some of those used in clinical research.Sharing links are not available for this article. The distribution is largely determined by the magnitude of the regional blood flow, and is therefore dependent on the degree of physical activity. (C157) In order to obtain the cumulated activities in different organs when the thyroid has been blocked, the transfer between the compartments representing inorganic iodide in the thyroid to the compartment for organically bound iodine is set to zero. In the normal case, total body retention is described by a mono-exponential function with a half-time of 100 min, fraction excreted by the kidneys of 1.0, and renal transit time of 5 min.Some society journals require you to create a personal profile, then activate your society account(C90) Current ICRP dosimetric models do not permit calculations of dose from breast as a source organ, and because the doses are likely to be very small, the Task Group does not consider it necessary to develop a new dosimetric model in which breast is treated as a source organ.© 2015 ICRP. av Icrp.
Organ uptake is mainly a function of molecular size, with the intact molecule showing uptake mainly in liver and bone marrow, while smaller fragments concentrate to a greater degree in the kidneys. However, even in this case, absorbed doses to other organs and tissues are calculated under the assumption that the radionuclide is distributed uniformly throughout both kidneys; this is justified because, in practice, use of a non-uniform distribution when calculating the absorbed doses to other organs and tissues results in very small changes (<10%) in the results obtained. ICRP Publications. ICRP, 2015b. monoclonal antibodies and brain receptor substances).
ICRP Publication 125. Cool , E. Lazo , P. Tattersall, G. Simeonov, S. Niu Abstract - The use of technologies to provide security screening for individuals and objects has been increasing rapidly, in keeping with the significant increase in security concerns worldwide. More detailed and patient-specific dosimetry and dose planning should be applied for therapeutic application of radionuclides.With institutional access I can:(66) The presence of chemical forms of the radionuclide other than that intended may change the distribution and kinetics of the radionuclide. METHODS FOR CALCULATING ABSORBED DOSE; 6. (31) It is often possible to reduce the absorbed dose to a patient by increasing the rate of elimination of the radionuclide from the body, for example by more frequent emptying of the urinary bladder (with hydration, diuretics, and catheterisation), the bowel (with laxatives and enemas), and the gallbladder (with a meal of high fat content and cholecystokinin). (57) Effective dose can be of practical value for comparing doses related to stochastic effects from: different diagnostic examinations and interventional procedures; the use of similar technologies and procedures in different hospitals and countries; and the use of different technologies for the same medical examination, provided that the representative patients or patient populations for which the effective doses are derived are similar with regard to age and gender.